Colchicine (brand names include: Goutnil) is an alkaloid of Colchicum autumnale L., Liliaceae as well as of many other species of the Liliaceae family.

Colchicine has been used for many centuries in the treatment of gout and more recently as a general anti-inflammatory agent and in the treatment of Familial Mediterranean Fever.

Colchicine has also been used to manage other conditions, including:

amyloidosis
Behcet's disease
dermatitis herpetiformis
Paget's disease
pericarditis
pseudogout
biliary and hepatic cirrhosis

Although Colchicine is considered highly effective for treating acute gouty arthritis, it is not effective for all types of pain. Colchicine is not considered an analgesic (painkilling) drug.

Colchicine is widely investigated for the treatment of COVID-19 due to its antiviral, anti-inflammatory and cardioprotective properties.

Recommendations

Follow the directions for using this medicine provided by your doctor. Take Colchicine exactly as directed.

The usual dose to relieve a gout attack is 1 to 1.2 mg (two 0.5 mg or two 0.6 mg tablets). This dose may be followed by one unit of either strength tablet every hour, or two units every two hours.

After the initial dose, it is sometimes sufficient to take 0.5 or 0.6 mg every two or three hours. The drug should be stopped if there is gastrointestinal discomfort or diarrhea.

In patients who have less than one gout attack per year, the usual dose is 0.5 or 0.6 mg per day, three or four days a week. For those who have more than one attack per year, the usual dose is 0.5 or 0.6 mg daily. Severe cases may require two or three 0.5 mg or 0.6 mg tablets daily.

Precautions

Tell your doctor before taking Colchicine, if:

you are allergic to any medicines;
you have any serious medical conditions;
you are pregnant or breast-feeding.

Ingredients

Active ingredient: colchicine.